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RespirAct™
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Designate a target PaCO2 ?
Designate a target PetO2 Breath-to-breath PetCO2 variability in the steady state Time to achieve a steady state Maintain steady increase in PCO2 Maintain steady change in PO2 Automated gas targeting and analysis Breathing circuit Cost |
NO. Only controls inspired PCO2. PaCO2 depends also subject ventilatory response and highly variable end-tidal to arterial difference (both unpredictable).
NO. ~ 4 mmHg Many minutes Dual exponential equilibration with the first exponential time constant ~2 min, and the second ~hours Only possible for normoxia; if another PO2 is targeted, it changes rapidly for about 1 min and reaches a steady state within ~6-9 min Manual switching by attendant in scanner with patient. Requires custom computer programming for analysis or manual analysis
Circuit of Figure 1A: 14 components:
Estimated cost:
Circuit of Figure 1B:
Estimated Cost: Capital and up front cost: $25,000 Cost per case: $100 (including in room attendant, not counting time for gas data analysis) |
YES. Can target within 2 mmHg, often within 1 mmHg (11)
YES ~ 1 mmHg 1-3 breaths Target is maintained within 1 mmHg, and sustained for any duration A target PO2 is reached within 2-3 breaths and remains steady within 1 mmHg of target Targets and durations are a sequence set in the control room computer. No attendant is required in the scanner
RespirAct™,
Cost
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